Browsing by Author "Tezer, N"
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Ab initio molecular structure study of alkyl substitute analogues of Alzheimer drug phenserine: structure-activity relationships for acetyl- and butyrylcholinesterase inhibitory action
Tezer, N (ELSEVIER SCIENCE BV, 2005)Considerable experimental evidence suggests that phenserine and some alkyl analogues show inhibitory action against human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The electronic structure of the newly ... -
Mechanisms and transition structures for conjugate and carbonyl addition of ammonia to three small alpha,beta-unsaturated carbonyl compounds. An ab initio molecular orbital study
Transition structures for the addition of ammonia to s-cis and s-trans acrolein, methyl vinyl ketone, and 2-butenal have been located with ab initio molecular orbital calculations. Optimization of the geometries of reactants, ... -
Structure-activity relationship studies on aza analogues of illudins
Illudin S and illudin M are extremely cytotoxic sesquiterpenes produced in cultures of basdiomycete Omphalotus illudins. Some of the analogues of illudins have been found to be quite effective at inhibiting tumor growth, ...